Principle
The powder raw material and adhesive in a cylinder are fully mixed at the bottom to become a humid soft material. Then it is cut by high-speed cutter and become uniform granules.
Every parts of the equipment
The Pharmaceutical powder blender high shear mixer is therefore the perfect partner for a Fluid Bed Dryer for optimum economy.
Pellets can be manufactured if the vertical granulator is combined with a Spheronizer/Pelletizer for subsequent spheronization of the granules.
Single-Pot systems also provide the facility to dry the granulate.
For the use of organic solvents, the high shear mixer can be combined with a special Pharmaceutical powder blender system with integral solvent recovery.
Cuting and Mixing blade
Due to the consistent modular design, the system can be configured individually and easily adapted to the constructional circumstances and specific requirements.
The heart of the Pharmaceutical powder blender Vertical Granulator is the patented Z-shaped rotor blade. This and various product-optimized chopper designs are the result of many years of successful development and cooperation with the Japanese specialist, Powrex.
Working Chamber
For non-sticky products in campaign production. Also for various processes with different accessory configurations. In this case, nozzles and additional equipment can be mounted to the lid.
For sticky products and similar processes with identical accessory configurations.
Handing device
This device can easily be integrated into horizontal or vertical product flow.
The high shear mixer can be charged manually by means of containers with lift and transporter devices (or charging stations) or pneumatically by means of suction conveyor systems.
The granulate is discharged from the working vessel into a fluid bed machine or a container, either by gravity or by means of pneumatic conveyors.
A Rotor Mill is often used downstream in order to achieve a homogeneous granulate spectrum.
Control System
As complex as necessary, as easy to use as possible. The controls are precisely adapted to your requirements. Thanks to their standardised hardware basis, the control systems can be retrofitted at any time, should your requirements change.
Intuitive graphical operating system
This new state-of-the-art control system embodies a uniquely intuitive graphical operating philosophy. It is designed to be as easy to use as possible and only be as complex as absolutely necessary, helping to make the control of every process clear and safe. All information required is displayed on a generous touch screen at all times. An animated flow diagram representation as well as an explosion-proof version are available.
Thin client technology
Pharmaceutical powder blender View comes with a central PC control unit with centralised data management. Therefore it is easy to connect multiple control units for one system or to visualise various units on a single screen.
High operating reliability
Proven Pharmaceutical powder blender PLC are employed. UPS battery buffered PC system
Flow chart of Jacket
Features
1.The machine adopts horizontal cylinder structure, its structure reasonable.
2.Air filled seal shaft for to drive. When washing , it can be changed to water.
3. Fluidized granulation, the granule is around ball shape. Its flow ability is good.
4.Compared to traditional process, 25% of adhesive can be reduced and the drying time is short.
5.The dry mixing time is 2 minutes and the granulating time is 1-4 minutes. Compared to the traditional process , 4-5
times of efficiency is raised.
6.Dry mixing, humid mixing and granulating are finished in the same sealed container. It is in conformity with the
requirements of GMP.
7.The whole operation has strict safe and protective measures.
8. Jacket type might be adopted on request
Technical parameters (Standard Type)
Overall dimensions
Equipment Picture
Many years of experience, successful cooperation and innovative development form the basis for the reliability of Pharmaceutical powder blender high shear mixers (also forced, moist or wet blenders or vertical granulators).
Pharmaceutical powder blender high shear mixers allow extremely fast granulation, which is gentle on the product, with high granulate densities and very good particle stability.